PCR Tests
On this page you will find information about key PCR tests that we offer
Analysis of AZF Y‑chromosome microdeletions
AZF deletions — the second most common genetic cause of male infertility after karyotype abnormalities
Sperm development is regulated by specific genes located on the short arm of the Y‑chromosome — the so‑called AZF region
Loss (deletion) of a segment in this area disrupts spermatogenesis, which can cause male infertility.
The AZF region is divided into three key segments: AZFa, AZFb and AZFc — each plays an important role in the formation of mature sperm cells.
Testing for AZF deletions not only helps to identify the cause of male infertility but also determines the possibility of obtaining sperm surgically. This is required for IVF programs in couples. In case of a deletion in AZFc it is possible to retrieve sperm for fertilization. With deletions in AZFa or AZFb, healthy sperm cannot be obtained and donor sperm is required.
What is a deletion?
Deletion — a type of chromosomal mutation in which a DNA fragment is lost. In male infertility, deletions affecting specific regions of the Y‑chromosome are most significant.
What is AZF?
AZF (Azoospermia Factor) — a region of the Y‑chromosome containing genes necessary for normal spermatogenesis, i.e. the formation of male germ cells. Damage to this region, especially in the form of deletion, can lead to absence of sperm in ejaculate (azoospermia) and, consequently, infertility.
How to take the test
You can take the test at our collection point at:
Tashkent, 1st Rakatboshi passage, 17
Blood collection takes no more than 10 minutes. Results are available online or in print.
PCR tests in the Genscreen Laboratory
International experience
Experts with years of practice in genetics, laboratory diagnostics and bioinformatics.
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We strictly follow the privacy policy: information is not shared with third parties without consent.
Personal consultation
Online consultation is available to explain results after the study.
Reliability and control
Every research stage is under strict supervision and multiple checks.
Technological leadership
Modern equipment and international diagnostic standards.
Transparent pricing
Clear costs without hidden fees, with the option to choose the most suitable test.